Opioid Stewardship Accelerator

  • Method: Accelerate Learnings
  • Impact Area: Improving Mental Wellness

Enhancing Treatment with Understanding, Efficacy and Dignity

CaroNova is supporting and aligning treatment providers in advancing best practices to prevent and treat opioid use disorder and scaling them across the Carolinas.

CaroNova launched the Opioid Stewardship Accelerator (OSA) in 2022 to support hospitals and health systems responding to the devastating opioid epidemic that persists across the Carolinas. The OSA is ultimately intended to catalyze the communitywide collaboration and systems changes necessary to improve health outcomes.

Where We Are

CaroNova reached several milestones through the Opioid Stewardship Accelerator between 2023 and 2025. In February 2023, CaroNova launched a virtual library featuring evidence-based and promising opioid stewardship strategies for health systems. CaroNova also provided implementation technical assistance by responding to hospital inquiries about adopting library strategies, supporting nine hospitals in adopting or expanding emergency department (ED)–based buprenorphine programs, and hosting two webinars highlighting successful opioid stewardship approaches and library resources.

The Online Library for Opioid Stewardship is a curated collection of best-practice tools and resources assembled by subject matter experts from across North and South Carolina. Developed through the Accelerator, the library was designed to support healthcare professionals in the prevention, intervention, and treatment of opioid use disorder (OUD).

Where We're Going

While the broader Opioid Stewardship Accelerator initiative itself is no longer in active development, CaroNova continues to maintain the Online Library for Opioid Stewardship as a reference resource for healthcare organizations seeking evidence-informed strategies for OUD prevention, treatment, and recovery. The library aligns with broader efforts led by partners such as the SC Center of Excellence in Addiction and the NC Division of Public Health and complements priorities supported through opioid settlement funding strategies in both states. Additional outputs from the Accelerator include an ED-based buprenorphine toolkit developed with the South Carolina Hospital Association and the SC Center of Excellence in Addiction.

Our Partners

Online Library for Opioid Stewardship

The CaroNova team engaged in co-design process in 2022 with subject matter experts (SMEs) from across the Carolinas to develop the Online Library for Opioid Stewardship. These SMEs were key collaborative partners in bistate convenings to codesign the library and associated technical assistance. The participating SMEs were from:

ED Buprenorphine Support for the Carolinas

Hospital sites that participated in the ED Buprenorphine Support for the Carolinas program in 2024 received an intensive series of trainings and implementation assistance to learn how to implement an ED-buprenorphine program and address site-level barriers. CaroNova partnered with Bridge, a program of the Public Health Institute, to provide the trainings and technical assistance. The hospital sites were:

SC Implementation Toolkit for Emergency Department Buprenorphine Treatment

This toolkit brings together best practices from emergency department (ED)-based buprenorphine treatment models across South Carolina. It is designed to support SC hospitals and ED clinicians in implementing or expanding buprenorphine programs by providing practical tools, recommended workflows, implementation checklists, and key considerations for connecting patients to ongoing outpatient care. The toolkit also highlights the important role EDs and outpatient treatment providers play as critical access points within the behavioral health system.

Sharing Results & Best Practices

CaroNova’s approach to pioneering lasting real-world health solutions is systematic, research-driven, collaborative, and community-minded. We purposely identify opportunities where partners can work together to cultivateco-design, and catalyze health improvements in the Carolinas through our process.

Resources

Online Library for Opioid Stewardship

Introduction to the Library

SC Implementation Toolkit for Emergency Department Buprenorphine Treatment

The Latest

Interested In Partnering With Us?

CaroNova brings together healthcare leaders, policymakers, community organizations, and investors to tackle the Carolinas’ most pressing health challenges.

We are always interested in opportunities to bring partners and resources together, support a robust change management process, and provide technical assistance to drive innovation. If you would like to learn more about working with us, please reach out below.

Let’s Create Lasting Change in Healthcare.